Milk Thistle Extract

Milk thistle extract is derived from the seeds of milk thistle (Silybum marianum (L.) Gaertn.)

Found In
  • Dietary supplements
  • Energy drinks
  • Herbal remedies
Also Known As
  • Silymarin
The Beverage Bottom Line

Milk thistle extract is authorized for use in the U.S., Europe and Canada.

This ingredient may have authorizations in countries not included on this site.


International Assessments and Authorizations


U.S. Food And Drug Administration

Generally recognized as safe for intended uses. ()

The aerial parts and seed oil of Silybum marianum, an extract from the fruit of Silybum marianum (extracted with acetone which contains 70 to 80% silymarin), are not novel in foods.

In 2018, European Medicines Agency (EMA) evaluated Silybum marianum (L.) Gaertn, fructus for traditional medicinal use.

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Joint FAO/WHO Expert Committee on Food Additives

Milk thistle extract is an ingredient, not a food additive.

Permitted for use as a supplemental ingredient. Ingredient has a history of safe use as a food.

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This page was last updated on 6/30/2025