Methylliberine

Methylliberine is a caffeine metabolite present at low levels in various Coffea plants that may serve as a stimulant.

Found In
  • Beverages
  • Dietary supplements
  • Energy supplements
  • Pre-workout products
Also Known As
  • Dynamine
  • 2-Methoxy-1,7,9-Trimethylpurine-6,8-Dione
The Beverage Bottom Line

Methylliberine is authorized for use in the U.S. Methylliberine has not yet been evaluated for use in beverages in either Europe or Canada.

This ingredient may have authorizations in countries not included on this site.

International Assessments and Authorizations

U.S. Food And Drug Administration

Generally recognized as safe for intended uses. ()

European Food Safety Authority

Not yet evaluated.

Joint FAO/WHO Expert Committee on Food Additives

Not yet evaluated.

Health Canada has authorized methylliberine for use as a natural health product.

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This page was last updated on 6/30/2025