L-lysine is an essential amino acid that plays a role in protein synthesis and immune function. It can be used as a nutrient. Protein-rich plant and animal-based foods high in lysine include dairy product, eggs, fish, lentils and meat.
L-Lysine
Found In
- Beverages
- Dietary supplements
- Fortified meal replacement beverages
- Fortified powdered drinks
Also Known As
- Lysine Hydrochloride
- Lysine Monohydrochloride
The Beverage Bottom Line
L-lysine is authorized for use in the U.S., Europe and Canada.
This ingredient may have authorizations in countries not included on this site.
International Assessments and Authorizations

U.S. Food And Drug Administration (FDA)
Generally recognized as safe for intended uses. (GRAS FDA-Notified)

European Food Safety Authority (EFSA)
Safe for intended uses. Permitted for addition in dietetic foods.

Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Safe for intended uses.
In 2007, WHO published a Technical Report on Protein and Amino Acid Requirements in Human Nutrition.

Health Canada
Safe for intended uses. Permitted as a supplemental ingredient.
In 2005 and 2006, dietary reference intakes for L-lysine were reviewed by the National Academies of Sciences, Engineering and Medicine.
This page was last updated on 6/30/2025.